Longitudinal Cortical Development During Adolescence and Young Adulthood in Autism Spectrum Disorder: Increased Cortical Thinning but Comparable Surface Area Changes
نویسندگان
چکیده
منابع مشابه
Accelerated longitudinal cortical thinning in adolescence
It remains unclear if changes of the cerebral cortex occur gradually from childhood to adulthood, or if adolescence marks a differential period of cortical development. In the current study of 90 healthy volunteers aged 5-32years (48 females, 85 right handed) with 180 scans (2 scans for each participant with ~4year gaps), thinning of overall mean thickness and across the four major cortical lob...
متن کاملDevelopment of cortical thickness and surface area in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder often associated with changes in cortical volume. The constituents of cortical volume - cortical thickness and surface area - have separable developmental trajectories and are related to different neurobiological processes. However, little is known about the developmental trajectories of cortical thickness and surface area in ASD. ...
متن کاملIncreased gyrification, but comparable surface area in adolescents with autism spectrum disorders.
Autism spectrum disorders are associated with atypically excessive early brain growth. Recent studies suggest that later cortical development, specifically cortical thickness, during adolescence and young adulthood is also aberrant. Nevertheless, previous studies of other surface-based metrics (e.g. surface area and gyrification) at high-resolution in autism spectrum disorders are limited. Fort...
متن کاملLongitudinal changes in cortical thickness in autism and typical development.
The natural history of brain growth in autism spectrum disorders remains unclear. Cross-sectional studies have identified regional abnormalities in brain volume and cortical thickness in autism, although substantial discrepancies have been reported. Preliminary longitudinal studies using two time points and small samples have identified specific regional differences in cortical thickness in the...
متن کاملAnterior Cortical Development During Adolescence in Bipolar Disorder.
BACKGROUND Increasing evidence supports a neurodevelopmental model for bipolar disorder (BD), with adolescence as a critical period in its development. Developmental abnormalities of anterior paralimbic and heteromodal frontal cortices, key structures in emotional regulation processes and central in BD, are implicated. However, few longitudinal studies have been conducted, limiting understandin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Academy of Child & Adolescent Psychiatry
سال: 2015
ISSN: 0890-8567
DOI: 10.1016/j.jaac.2015.03.007